Nursing Case Study

A 36-year-old female has a routine physical. She is single, doesn’t smoke and has a few drinks of alcohol a week. She began menarche at age 11 and her first sexual intercourse was at age 14. She has had numerous sexual partners and does not regularly use barrier contraception. Physical examination is normal. The Pap smear comes back as atypical squamous cells of undetermined significance (ASCUS).

a. What risk factors does she have for cervical cancer?

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b. Describe the pathogenesis of Human Papilloma Virus.

c. Why should HPV testing be done and what are the tests to be ordered?

d. What HPV subtypes are associated with cervical cancer?

e. Explain the role of E6 and E7 HPV proteins in cervical cancer.

f. Differentiate between Human Papilloma Virus and Herpes Simplex virus

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